Tapentadol is partly metabolized because of the hepatic enzymes CYP2C9, CYP2C19, and CYP2D6 so it innately has interactions with prescription drugs that enhance or repress the exercise/expression of one or more of those enzymes, along with with substrates of these enzymes (resulting from competition with the enzyme); some enzyme mediators/substrates https://romainj737cjn0.wikigdia.com/user