Much like a Coronary angiogram, a high-quality gentle tube is inserted through your wrist or groin and placed close to the center below x-ray assistance.  ED brings about endothelial mobile activation, which leads to improved expression of adhesion molecules, activation of platelets and inflammatory cells, and increased permeability of endothelial cells; https://www.sgvascularctr.com/all-things-vascular-singapore-guide/